Prairie Cannabis Chicago - South Loop

A Recreational Dispensary in Chicago, IL

NOW OPEN IN THE SOUTH LOOP! Located in the heart of Chicago’s South Loop, Prairie Chicago South Loop is your premier destination for high-quality cannabis products at unbeatable value. Whether you’re a seasoned enthusiast or new to cannabis, our friendly and knowledgeable team is here to guide you. Experience top-tier flower, edibles, vapes, and more—all with the convenience and customer service you deserve..

Store Hours: Monday 10:00 AM - 6:00 PM Tuesday 11:00 AM - 9:00 PM Wednesday 11:00 AM - 9:00 PM Thursday 11:00 AM - 9:00 PM Friday 11:00 AM - 9:00 PM Saturday 11:00 AM - 9:00 PM Sunday 11:00 AM - 9:00 PM